SCHEMBL410485

SCHEMBL410485

OBOc1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.54
LMNA P02545 3/20 0.54
MAPT P10636 3/20 0.54
JAK2 O60674 1/20 0.54
CA2 P00918 2/20 0.52
TP53 P04637 2/20 0.52
CA1 P00915 1/20 0.52
TSHR P16473 1/20 0.52
HPGD P15428 3/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 2/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187855 0.82 CA2 (0.54) GAALMNAMAPTJAK2CA2
SCHEMBL11320622 0.78 TSHR (0.50) GAALMNAMAPTJAK2CA2
SCHEMBL15501054 0.78 CA2 (0.56) GAALMNAMAPTJAK2CA2
SCHEMBL10035451 0.73 L3MBTL1 (0.42) GAALMNAHPGDALDH1A1KDM4E
SCHEMBL14925378 0.73 MEN1 (0.43) LMNAMAPTTP53TSHRHPGD
SCHEMBL17563713 0.73 FABP7 (0.35) GAALMNAMAPTJAK2CA2
SCHEMBL365525 0.73 ALDH1A1 (0.50) GAALMNAMAPTTSHRALDH1A1
SCHEMBL1638392 0.73 CA1 (0.62) LMNAMAPTCA2TP53CA1
SCHEMBL9132 0.73 KDM4E (0.46) LMNATSHRALDH1A1KDM4EALOX15
SCHEMBL14926315 0.73 HTR7 (0.42) GAALMNAMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994216-A 2-Boron ester-norbornene and use thereof and polymer containing alkenyl boron ester in main chain 北京大学 2024-11-22 CN claimed
US-5741870-A HAVING AT LEAST ONE BORONIC ACID ESTER GROUP BONDED TO AN SP3 CARBON ATOM OF THE POLYOLEFIN KURARAY CO., LTD. (JP) 1998-04-21 US claimed
US-20240239816-A1 BORONO-PHENYLALANINE DERIVATIVE STELLA PHARMA CORPORATION (JP) 2024-07-18 US disclosed
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD (KR) 2024-06-27 US disclosed
WO-2024100095-A1 COMPOUNDS AND THEIR USE KING’S COLLEGE LONDON (GB) 2024-05-16 WO disclosed
EP-4361159-A1 BORONO-PHENYLALANINE DERIVATIVE Stella Pharma Corporation (JP) 2024-05-01 EP disclosed
EP-4302830-A2 QUINAZOLINE DERIVATIVES USED TO TREAT HIV Gilead Sciences, Inc. (US) 2024-01-10 EP disclosed
US-11814393-B2 Substituted guanidine compounds UBE CORPORATION (JP) 2023-11-14 US disclosed
WO-2023190878-A1 TETRAHYDRONAPHTHALENE DERIVATIVE Atransen Pharma株式会社 2023-10-05 WO disclosed
EP-3960735-B1 QUINAZOLINE DERIVATIVES USED TO TREAT HIV GILEAD SCIENCES INC (US) 2023-09-13 EP disclosed
US-20230150974-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
EP-1228850-A1 Method for producing ethylene-vinyl alcohol copolymer resin composition KURARAY CO., LTD. (JP) 2002-08-07 EP disclosed
US-6398059-B1 Fuel container KURARAY CO., LTD. (JP) 2002-06-04 US disclosed
EP-1166892-A2 A method of producing a shaped article having excellent barrier properties Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed
EP-1108653-A1 FUEL CONTAINER KURARAY CO., LTD. (JP) 2001-06-20 EP disclosed
EP-0616010-B1 Resin composition KURARAY CO (JP) 1998-11-04 EP disclosed
US-5741870-A HAVING AT LEAST ONE BORONIC ACID ESTER GROUP BONDED TO AN SP3 CARBON ATOM OF THE POLYOLEFIN KURARAY CO., LTD. (JP) 1998-04-21 US disclosed
US-5571871-A Resin composition KURARAY CO., LTD. (JP) 1996-11-05 US disclosed
US-5466748-A Resin composition KURARAY CO., LTD. (JP) 1995-11-14 US disclosed
EP-0616010-A2 Resin composition KURARAY CO., LTD. (JP) 1994-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CCNL2, UBE2L3 GAA 3747/4885LMNA 1970/4885MAPT 3527/4885
US-20230150974-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB GAA 9/4885LMNA 225/4885MAPT 2074/4885
US-20240239816-A1 BORONO-PHENYLALANINE DERIVATIVE SLC7A1, SLC1A5, LATS2 GAA 490/4885LMNA 2635/4885MAPT 874/4885
US-11814393-B2 Substituted guanidine compounds GMPS, PDE3B, GUCY1A2 GAA 56/4885LMNA 1713/4885MAPT 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.