SCHEMBL3655680

SCHEMBL3655680

O=C(O)c1ccc2c(c1)C(=O)OC21c2cc(F)c(O)c(F)c2Oc2c1cc(F)c(O)c2F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.43
GNB1 P62873 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RECQL P46063 2/20 0.43
BLM P54132 2/20 0.43
ACE2 Q9BYF1 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
PRMT1 Q99873 2/20 0.43
USP2 O75604 2/20 0.43
THRB P10828 1/20 0.43
CDK2 P24941 1/20 0.43
CHAT P28329 1/20 0.43
BLVRB P30043 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
FTO Q9C0B1 8/20 0.42
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7970054 0.86 GNG2 (0.40) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL16980187 0.85 KCNH2 (0.40) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL7970168 0.83 FTO (0.60) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL16984106 0.83 GSTP1 (0.44) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL1942341 0.83 MEN1 (0.61) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL16984107 0.81 KCNH2 (0.41) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL16984054 0.80 GAA (0.36) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL3648893 0.80 FTO (0.47) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL203192 0.79 GNG2 (0.43) GNG2GNB1MEN1KMT2ARECQL
SCHEMBL16980185 0.79 GNG2 (0.41) GNG2GNB1MEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230120665-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX LIFE TECHNOLOGIES CORP (US) 2023-04-20 US disclosed
US-11585819-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical VERSITECH LIMITED (CN) 2023-02-21 US disclosed
US-11585819-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical VERSITECH LIMITED (CN) 2023-02-21 US disclosed
US-20210096142-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL VERSITECH LIMITED (CN) 2021-04-01 US disclosed
US-20210096142-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL VERSITECH LIMITED (CN) 2021-04-01 US disclosed
US-10877051-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical THE UNIVERSITY OF HONG KONG (CN) 2020-12-29 US disclosed
US-10877051-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical THE UNIVERSITY OF HONG KONG (CN) 2020-12-29 US disclosed
EP-3099680-B1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL UNIV HONG KONG (CN) 2020-08-12 EP disclosed
US-20190242912-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX Life Technologies Corporation 2019-08-08 US disclosed
US-20170067918-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX Life Technologies Corporation 2017-03-09 US disclosed
US-20150219676-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL VERSITECH LIMITED (CN) 2015-08-06 US disclosed
WO-2015113455-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL THE UNIVERSITY OF HONG KONG (CN) 2015-08-06 WO disclosed
US-20150104823-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX Life Technologies Corporation 2015-04-16 US disclosed
EP-2201367-B1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX LIFE TECHNOLOGIES CORP (US) 2013-03-20 EP disclosed
EP-2562543-A1 Composition and method for measuring thallium influx and efflux Life Technologies Corporation (US) 2013-02-27 EP disclosed
US-20100279314-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX Life Technologies Corporation 2010-11-04 US disclosed
EP-2201367-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX Life Technologies Corporation (US) 2010-06-30 EP disclosed
WO-2009052183-A1 COMPOSITION AND METHOD FOR MEASURING THALLIUM INFLUX AND EFFLUX INVITROGEN CORPORATION (US) 2009-04-23 WO disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11585819-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical SQOR, MT-ND4, COX6A1 GNG2 2410/4885GNB1 1720/4885MEN1 4228/4885
US-10877051-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical SQOR, MT-ND4, COX6A1 GNG2 2422/4885GNB1 1746/4885MEN1 4073/4885
US-20210096142-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL SQOR, MT-ND4, COX6A1 GNG2 2422/4885GNB1 1746/4885MEN1 4073/4885
US-20150219676-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL SQOR, MT-ND4, COX6A1 GNG2 2422/4885GNB1 1746/4885MEN1 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.