Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3651075 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP2C19MEN1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3653064 | 0.87 | KDM4E (0.42) | MLYCDCYP1A2CYP2C19KMT2ANPC1 | |
| SCHEMBL3658110 | 0.85 | KDM4E (0.44) | CYP1A2CYP2C19KMT2ANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3650317 | 0.84 | EPHX2 (0.43) | CYP1A2CYP2C19MEN1KMT2ATDP1 | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.83 | RAB9A (0.45) | KMT2ANPC1RAB9AMAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3657679 | 0.83 | RAB9A (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3658726 | 0.82 | CYP1A2 (0.44) | CYP1A2CYP2C19MEN1KMT2ANPC1 | |
| SCHEMBL3658418 | 0.82 | NPC1 (0.48) | MEN1KMT2ANPC1MAPTGAA | |
| Trifluoroacetic Acid SCHEMBL3657521 | 0.82 | MEN1 (0.42) | MEN1KMT2ATDP1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |