Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3659581 | 0.89 | CA12 (0.41) | CA12CA9NPC1RAB9ACA1 | |
| Trifluoroacetic Acid SCHEMBL3656579 | 0.81 | BCL9 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL3657521 | 0.80 | MEN1 (0.42) | NPC1RAB9AKDM4ESMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL3657679 | 0.78 | RAB9A (0.46) | NPC1RAB9AKDM4ESMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.78 | — | — | |
| Trifluoroacetic Acid SCHEMBL3652245 | 0.77 | NPC1 (0.39) | NPC1RAB9AKDM4ESMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL3653109 | 0.77 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.77 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2KMT2ATP53 | |
| Trifluoroacetic Acid SCHEMBL3650317 | 0.77 | EPHX2 (0.43) | NPC1RAB9AKDM4ESMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL3652805 | 0.77 | KDM4E (0.41) | NPC1RAB9AKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |