Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365721 | 0.83 | ALDH1A1 (0.45) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL365775 | 0.82 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1KDM4EAPAF1 | |
| SCHEMBL365826 | 0.81 | KMT2A (0.48) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL367707 | 0.77 | EGFR (0.44) | PTGDR2MEN1KMT2AAGTR1RORC | |
| SCHEMBL367747 | 0.77 | AGTR1 (0.48) | PTGDR2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL366104 | 0.75 | CA9 (0.46) | MEN1KMT2AALDH1A1KDM4EAPAF1 | |
| SCHEMBL366693 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL366858 | 0.71 | KMT2A (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL365427 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL365400 | 0.71 | ELANE (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |