Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 8/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | POLR1A | O95602 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365522 | 0.89 | MEN1 (0.41) | ALDH1A1MEN1KMT2AHTR6GAA | |
| SCHEMBL366133 | 0.86 | AGTR1 (0.41) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL364606 | 0.85 | HTR6 (0.38) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL366692 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1KMT2AHTR6 | |
| SCHEMBL364887 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL366408 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2AHTR6 | |
| SCHEMBL366312 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365839 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365801 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365411 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |