Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367747 | 0.89 | AGTR1 (0.48) | EGFRAGTR1PTGDR2MEN1KMT2A | |
| SCHEMBL365826 | 0.85 | KMT2A (0.48) | EGFRSRCMEN1KMT2ALMNA | |
| SCHEMBL366999 | 0.85 | EGFR (0.42) | EGFRSRCMEN1KMT2ALMNA | |
| SCHEMBL366741 | 0.81 | EGFR (0.38) | EGFRSRCAGTR1MEN1KMT2A | |
| SCHEMBL367764 | 0.79 | EGFR (0.45) | EGFRSRCMEN1KMT2AHTR2A | |
| SCHEMBL367201 | 0.79 | EGFR (0.45) | EGFRSRCAGTR1HTR2AHTR2C | |
| SCHEMBL367330 | 0.78 | EGFR (0.46) | EGFRSRCKMT2AHTR2AHTR2C | |
| SCHEMBL366109 | 0.78 | EGFR (0.43) | EGFRSRCAGTR1HTR2AHTR2C | |
| SCHEMBL367706 | 0.78 | BAZ2B (0.41) | EGFRSRCMEN1KMT2APTGS2 | |
| SCHEMBL365722 | 0.77 | PTGDR2 (0.35) | AGTR1PTGDR2RORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |