SCHEMBL365850

SCHEMBL365850

CC(C)c1cc(C(C)C)c(-c2ccccc2I)c(C(C)C)c1.CCO[PH](=O)c1ccccc1-c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL365389 0.93 RXRA (0.32) RXRA
SCHEMBL16767933 0.82 RXRA (0.32) RXRA
SCHEMBL366603 0.79 GABRA1 (0.37)
SCHEMBL16311318 0.69 GABRA1 (0.35)
SCHEMBL28888574 0.69 SLC6A2 (0.32)
SCHEMBL7609167 0.68 FABP3 (0.41)
SCHEMBL366679 0.65 MEN1 (0.41) RXRA
SCHEMBL15200387 0.64 ROCK2 (0.33) RXRA
SCHEMBL9003442 0.64 ELANE (0.31)
SCHEMBL28926447 0.63 GABRA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593226-A1 PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS Abbvie Inc. (US) 2013-05-22 EP disclosed
WO-2012009698-A1 PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS ABBOTT LABORATORIES (US) 2012-01-19 WO disclosed