Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365389 | 0.88 | RXRA (0.32) | RXRARXRBRXRGRARAFABP3 | |
| SCHEMBL365850 | 0.82 | RXRA (0.32) | RXRA | |
| SCHEMBL7609167 | 0.72 | FABP3 (0.41) | FABP3FABP4 | |
| SCHEMBL366679 | 0.69 | MEN1 (0.41) | RXRARXRBRXRGRARA | |
| SCHEMBL15200387 | 0.69 | ROCK2 (0.33) | RXRARXRBRXRGRARA | |
| SCHEMBL16050486 | 0.67 | FABP3 (0.41) | RXRAFABP3FABP4 | |
| SCHEMBL28926436 | 0.67 | LMNA (0.44) | FABP3FABP4 | |
| SCHEMBL28438073 | 0.67 | GABRA1 (0.38) | FABP3FABP4 | |
| SCHEMBL20862831 | 0.67 | FABP3 (0.33) | FABP3FABP4 | |
| Phosphine SCHEMBL22634093 | 0.66 | GABRA1 (0.35) | FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152126-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE INC. | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152126-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | PHOSPHO1, PLCG2, PPIP5K2 | RXRA 3813/4885RXRB 3781/4885RXRG 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.