Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 9/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.36 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365964 | 0.92 | KDM4E (0.36) | GPR132METIKBKBCMKLR2CMKLR1 | |
| SCHEMBL364642 | 0.91 | CYP11B1 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL365081 | 0.85 | KDM4E (0.38) | IKBKBHTR1ADRD2KDM4EALDH1A1 | |
| SCHEMBL366015 | 0.84 | CYP11B1 (0.37) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL366072 | 0.83 | FFAR1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL365105 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL367670 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL367194 | 0.79 | GPR132 (0.38) | GPR132METIKBKBCMKLR2CMKLR1 | |
| SCHEMBL367346 | 0.77 | ALDH1A1 (0.37) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL366694 | 0.77 | MKNK1 (0.41) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |