Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365406 | 0.90 | STS (0.39) | CA1CA2CA9STSCA12 | |
| SCHEMBL367389 | 0.86 | IDO1 (0.36) | IDO1PTGS2KDM4EMEN1APAF1 | |
| SCHEMBL366019 | 0.86 | STS (0.41) | CA1CA2CA9IDO1STS | |
| SCHEMBL365212 | 0.80 | KMT2A (0.39) | IDO1PTGS2KDM4EMEN1APAF1 | |
| SCHEMBL367670 | 0.79 | ALDH1A1 (0.40) | IDO1PTGS2KDM4EMEN1APAF1 | |
| SCHEMBL366820 | 0.79 | IDO1 (0.43) | CA1CA2CA9IDO1PTGS2 | |
| SCHEMBL367244 | 0.78 | KDM4E (0.33) | IDO1KDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL367255 | 0.78 | PTGS2 (0.42) | IDO1PTGS2MAPT | |
| SCHEMBL367759 | 0.76 | STS (0.41) | CA1CA2CA9IDO1STS | |
| SCHEMBL365788 | 0.75 | BAZ2B (0.45) | IDO1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |