Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367244 | 0.90 | KDM4E (0.33) | IDO1ALDH1A1KDM4EMEN1APAF1 | |
| SCHEMBL365225 | 0.86 | CA12 (0.35) | IDO1PTGS2ALDH1A1KDM4EMEN1 | |
| SCHEMBL366115 | 0.86 | CA1 (0.41) | IDO1PTGS2ALDH1A1KDM4EMEN1 | |
| SCHEMBL366074 | 0.77 | POLB (0.33) | IDO1ALDH1A1KDM4EMEN1APAF1 | |
| SCHEMBL365406 | 0.77 | STS (0.39) | ALDH1A1KDM4EMEN1APAF1MAPT | |
| SCHEMBL367408 | 0.74 | EPHX1 (0.51) | KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL365212 | 0.74 | KMT2A (0.39) | IDO1PTGS2ALDH1A1KDM4EMEN1 | |
| SCHEMBL367390 | 0.74 | AGTR1 (0.34) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL367670 | 0.73 | ALDH1A1 (0.40) | IDO1PTGS2ALDH1A1KDM4EMEN1 | |
| SCHEMBL366019 | 0.73 | STS (0.41) | IDO1PTGS2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |