Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367333 | 0.86 | HPGD (0.52) | CNR2HPGDALDH1A1KMT2AKDM4E | |
| SCHEMBL365229 | 0.85 | HPGD (0.48) | CNR2HPGDALDH1A1KMT2AKDM4E | |
| SCHEMBL366173 | 0.84 | CNR1 (0.47) | ALDH1A1ALOX15RXFP1KMT2AMEN1 | |
| SCHEMBL365334 | 0.83 | L3MBTL1 (0.47) | CNR2HPGDALDH1A1ALOX15MGLL | |
| SCHEMBL364927 | 0.82 | SRC (0.51) | ALDH1A1KMT2AMEN1KDM4ETHRB | |
| SCHEMBL366310 | 0.81 | ALDH1A1 (0.52) | HPGDALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL364339 | 0.80 | KMT2A (0.49) | ALDH1A1KMT2AMEN1KDM4ETHRB | |
| SCHEMBL364281 | 0.80 | NR4A2 (0.48) | ALDH1A1KMT2AMEN1KDM4ETHRB | |
| SCHEMBL364265 | 0.77 | NR4A2 (0.46) | ALDH1A1KMT2AMEN1KDM4ETHRB | |
| SCHEMBL364450 | 0.77 | KMT2A (0.47) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |