Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367564 | 0.89 | HPGD (0.50) | ALDH1A1HPGDKDM4EMEN1RAB9A | |
| SCHEMBL365591 | 0.88 | HPGD (0.49) | ALDH1A1HPGDKDM4EMEN1RAB9A | |
| SCHEMBL365544 | 0.86 | REN (0.53) | — | |
| SCHEMBL366309 | 0.81 | KDM4E (0.55) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL365335 | 0.81 | CNR2 (0.47) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL365014 | 0.79 | KDM4E (0.48) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL365668 | 0.79 | KMT2A (0.55) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL364594 | 0.78 | EGFR (0.44) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL365565 | 0.78 | KMT2A (0.52) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL365101 | 0.78 | KMT2A (0.51) | KDM4EHSD17B10MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |