SCHEMBL4429904

SCHEMBL4429904

COc1[c]cc(C)c(-c2cc(I)ccc2Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669190 0.85 S100A4 (0.32)
SCHEMBL4439144 0.75 PLK4 (0.31)
SCHEMBL4429902 0.73
SCHEMBL3410427 0.71 ALDH1A1 (0.35)
SCHEMBL4439375 0.71 F11 (0.33)
SCHEMBL14371942 0.71 TGM2 (0.37)
SCHEMBL4437895 0.69 L3MBTL1 (0.33)
SCHEMBL360305 0.68 SQOR (0.44)
SCHEMBL221777 0.68 CA2 (0.35)
SCHEMBL3663442 0.68 MEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121660-A2 FUNGICIDAL AMIDES E. I. Du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
WO-2008091580-A2 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed