Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665359 | 0.91 | UTS2R (0.45) | UTS2RCHRNA7DRD4 | |
| SCHEMBL3659196 | 0.90 | RAB9A (0.39) | UTS2RCHRNA7DRD4 | |
| SCHEMBL647341 | 0.89 | UTS2R (0.52) | UTS2RDRD4SLC6A5 | |
| SCHEMBL3666382 | 0.88 | UTS2R (0.44) | UTS2RCHRNA7 | |
| SCHEMBL3667429 | 0.87 | SLC6A4 (0.40) | UTS2RDRD4F10SLC6A5 | |
| SCHEMBL3663526 | 0.86 | AR (0.40) | UTS2RCHRNA7DRD4 | |
| SCHEMBL4441003 | 0.85 | DRD4 (0.43) | DRD4F10SLC6A5 | |
| SCHEMBL3660163 | 0.85 | F10 (0.39) | DRD4F10SLC6A5 | |
| SCHEMBL3666339 | 0.85 | SLC6A4 (0.40) | UTS2RCHRNA7DRD4F10SLC6A5 | |
| SCHEMBL647404 | 0.84 | UTS2R (0.56) | UTS2RDRD4SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231600-A1 | CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS FOR METABOLIC DISORDERS | Rigel Pharmaceuticals, Inc. (US) | 2010-09-29 | — | — | EP | claimed |
| WO-2009065131-A1 | CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS FOR METABOLIC DISORDERS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | claimed |