Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364862 | 0.89 | EGFR (0.56) | EGFRSRCKDM4EMAPTHPGD | |
| SCHEMBL366454 | 0.83 | EGFR (0.44) | EGFRSRCKDM4EMAPTHPGD | |
| SCHEMBL366300 | 0.82 | CNR2 (0.38) | EGFRSRCHPGDALDH1A1HDAC1 | |
| SCHEMBL366186 | 0.81 | ALDH1A1 (0.39) | EGFRSRCHPGDALDH1A1HSD17B10 | |
| SCHEMBL366536 | 0.80 | EGFR (0.53) | EGFRSRCKDM4EMAPTHPGD | |
| SCHEMBL365488 | 0.80 | PARP1 (0.41) | EGFRSRCHPGDALDH1A1HDAC1 | |
| Potassium Ion SCHEMBL364977 | 0.78 | EGFR (0.51) | EGFRSRCKDM4EMAPTHPGD | |
| SCHEMBL361357 | 0.78 | EGFR (0.51) | EGFRSRCKDM4EMAPTHPGD | |
| SCHEMBL366838 | 0.78 | ALDH1A1 (0.41) | EGFRSRCKDM4EHPGDALDH1A1 | |
| SCHEMBL366239 | 0.78 | PLA2G2A (0.41) | HPGDALDH1A1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |