Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366109 | 0.88 | EGFR (0.43) | EGFRKDM4EALDH1A1POLBAGTR1 | |
| SCHEMBL364533 | 0.85 | NR4A2 (0.45) | EGFRKDM4EALDH1A1POLBSRC | |
| SCHEMBL366491 | 0.78 | EGFR (0.40) | EGFRKDM4EALDH1A1POLBHPGD | |
| SCHEMBL365775 | 0.78 | ALDH1A1 (0.32) | KDM4EALDH1A1NR4A2 | |
| SCHEMBL364219 | 0.78 | ALDH1A1 (0.47) | EGFRALDH1A1POLBHPGDSRC | |
| SCHEMBL365935 | 0.76 | KDM4E (0.47) | EGFRKDM4EALDH1A1POLBHPGD | |
| SCHEMBL366888 | 0.76 | EGFR (0.44) | EGFRKDM4EALDH1A1POLBHPGD | |
| SCHEMBL367747 | 0.76 | AGTR1 (0.48) | EGFRKDM4EALDH1A1POLBHPGD | |
| SCHEMBL366876 | 0.75 | EGFR (0.44) | EGFRKDM4EALDH1A1POLBHPGD | |
| SCHEMBL365779 | 0.74 | EGFR (0.43) | EGFRKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |