Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671725 | 0.84 | AR (0.37) | FABP3FABP4FABP5CCNCCDK8 | |
| Hydrochloric Acid SCHEMBL3664999 | 0.83 | AR (0.36) | FABP3FABP4FABP5CCNCCDK8 | |
| SCHEMBL1896069 | 0.82 | MTNR1A (0.38) | FABP3FABP4FABP5CCNCCDK8 | |
| SCHEMBL16113864 | 0.82 | TRPV1 (0.38) | SLC16A3KDM4EMAPTTSHRSLC6A2 | |
| SCHEMBL5315930 | 0.75 | TRPV1 (0.40) | SLC16A3ARKDM4EALDH1A1GAA | |
| SCHEMBL3669718 | 0.72 | FABP3 (0.38) | FABP3FABP4FABP5HSD17B1HSD17B2 | |
| SCHEMBL27603742 | 0.70 | SLC16A3 (0.39) | SLC16A3ARKDM4EALDH1A1GAA | |
| SCHEMBL8101979 | 0.68 | HTR2A (0.47) | HSD17B1HSD17B2SLC6A4ALOX5 | |
| Carbamic Acid SCHEMBL28108904 | 0.67 | SLC16A3 (0.41) | SLC16A3ARKDM4EALDH1A1GAA | |
| SCHEMBL27310886 | 0.66 | MTNR1A (0.43) | KDM4EALDH1A1GAAHSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2014159251-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | disclosed |