Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3664999 | 0.99 | AR (0.36) | ARFABP3FABP4FABP5CCNC | |
| SCHEMBL3665020 | 0.84 | FABP3 (0.38) | ARFABP3FABP4FABP5CCNC | |
| SCHEMBL1896069 | 0.77 | MTNR1A (0.38) | FABP3FABP4FABP5CCNCCDK8 | |
| SCHEMBL3669718 | 0.71 | FABP3 (0.38) | ARFABP3FABP4FABP5HSD17B1 | |
| SCHEMBL23450494 | 0.65 | GSTP1 (0.52) | ARCCNCCDK8HSD17B1HSD17B2 | |
| SCHEMBL16113864 | 0.65 | TRPV1 (0.38) | MAPK1MAPTRAB9ASLC6A2SLC6A4 | |
| SCHEMBL19034099 | 0.65 | RAB9A (0.42) | ARFABP3FABP4FABP5IKBKB | |
| SCHEMBL304872 | 0.63 | ALDH1A1 (0.39) | L3MBTL1MAPTSMN1; SMN2MTNR1A | |
| SCHEMBL24004127 | 0.63 | AR (0.44) | ARHSD17B1HSD17B2IKBKBL3MBTL1 | |
| SCHEMBL1133131 | 0.63 | IKBKB (0.54) | ARHSD17B1HSD17B2IKBKBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | disclosed |