Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896065 | 0.81 | FABP3 (0.38) | FABP3FABP4FABP5SLC6A2SLC6A4 | |
| SCHEMBL6237984 | 0.76 | LMNA (0.47) | CYP2D6TSHRKMT2AHIF1AEGFR | |
| SCHEMBL15939773 | 0.76 | LMNA (0.47) | CYP2D6TSHRKMT2AHIF1AEGFR | |
| SCHEMBL3665020 | 0.72 | FABP3 (0.38) | FABP3FABP4FABP5SLC6A2SLC6A4 | |
| SCHEMBL3671725 | 0.71 | AR (0.37) | FABP3FABP4FABP5SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3664999 | 0.70 | AR (0.36) | FABP3FABP4FABP5SLC6A2SLC6A4 | |
| SCHEMBL11261519 | 0.70 | LMNA (0.52) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL22288132 | 0.68 | LMNA (0.42) | CYP2D6MEN1CYP1A2TSHRKMT2A | |
| SCHEMBL5107136 | 0.66 | LMNA (0.61) | CYP2D6TSHRHIF1AL3MBTL1 | |
| SCHEMBL30172716 | 0.66 | LMNA (0.61) | CYP2D6TSHRHIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | claimed |
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | disclosed |