SCHEMBL366608

SCHEMBL366608

CCCCCNCCNCCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
ALDH1A1 P00352 3/20 0.56
AKR1B1 P15121 1/20 0.56
GPR84 Q9NQS5 7/20 0.54
PPARG P37231 7/20 0.54
PPARD Q03181 7/20 0.54
PPARA Q07869 7/20 0.54
HDAC11 Q96DB2 5/20 0.54
PTPN1 P18031 3/20 0.54
TLR2 O60603 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
FABP4 P15090 2/20 0.54
KMT2A Q03164 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SLC22A8 Q8TCC7 1/20 0.54
MEN1 O00255 1/20 0.54
ESR1 P03372 1/20 0.54
ALOX15 P16050 1/20 0.54
PDE4A P27815 1/20 0.54
PDE3A Q14432 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16147341 1.00 TSHR (0.56) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL30519206 0.98 GPR84 (0.58) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL30519223 0.98 GPR84 (0.58) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL11700572 0.98 GPR84 (0.58) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL7570178 0.98 GPR84 (0.58) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL674092 0.98 TSHR (0.59) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL148702 0.96 GPR84 (0.60) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL8437709 0.96 GPR84 (0.60) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL6758778 0.96 GPR84 (0.60) TSHRALDH1A1AKR1B1GPR84PPARG
SCHEMBL2749487 0.96 GPR84 (0.60) TSHRALDH1A1AKR1B1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288156-A1 AGENT FOR DYEING KERATINOUS MATERIAL, CONTAINING AT LEAST TWO ORGANOSILICON COMPOUNDS THAT ARE DIFFERENT FROM EACH OTHER, AT LEAST ONE PIGMENT AND AT LEAST ONE LIQUID FATTY COMPONENT AND/OR A SOLVENT Henkel AG & Co. KGaA (DE) 2023-12-13 EP disclosed
EP-3999016-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A COLORED EFFECT PIGMENT AND A FILM-FORMING POLYMER IV Henkel AG & Co. KGaA (DE) 2022-05-25 EP disclosed
EP-3999019-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A COATED EFFECT PIGMENT AND A FILM-FORMING POLYMER II Henkel AG & Co. KGaA (DE) 2022-05-25 EP disclosed
US-11324676-B2 Hydrogen peroxide formulations in barrier layer films with a metalized layer HENKEL AG & CO. KGAA (DE) 2022-05-10 US disclosed
US-20220040074-A1 Decolorization of Dyed Keratinic Fibers HENKEL AG & CO. KGAA (DE) 2022-02-10 US disclosed
US-11229587-B2 Hydrogen peroxide formulations in barrier layer films with a metallized layer HENKEL AG & CO. KGAA (DE) 2022-01-25 US disclosed
EP-3937889-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A MIXTURE OF SILICONES Henkel AG & Co. KGaA (DE) 2022-01-19 EP disclosed
US-20210361544-A1 HYDROGEN PEROXIDE FORMULATIONS IN BARRIER LAYER FILMS WITH A SiOx LAYER HENKEL AG & CO. KGAA (DE) 2021-11-25 US disclosed
EP-3897562-A1 AGENT FOR DYEING HAIR, CONTAINING AT LEAST ONE ORGANIC SILICON COMPOUND I Henkel AG & Co. KGaA (DE) 2021-10-27 EP disclosed
EP-3897862-A1 METHOD FOR DYEING KERATIN MATERIAL BY MEANS OF A DYEING AGENT AND AN ACIDIC POST-TREATMENT AGENT Henkel AG & Co. KGaA (DE) 2021-10-27 EP disclosed
US-20050009781-A1 Methods of skin treatment and use of water-soluble beta-(1,3) glucans as active agents for producing therapeutic skin treatment agents BIOTEC PHARMACON ASA (NO) 2005-01-13 US disclosed
US-20040255402-A1 Developer components and their use for dyeing keratinic fibers HENKEL AG & CO. KGAA (DE) 2004-12-23 US disclosed
EP-1478696-A1 PROCESS FOR THE PREPARATION OF CATIONIC AZO COMPOUNDS Ciba SC Holding AG (CH) 2004-11-24 EP disclosed
US-20040170670-A1 Cosmetic sponges REGENESIS LLC 2004-09-02 US disclosed
US-6706696-B1 MIXTURES OF SPECIFIC GLUCANS AND NUCLEIC ACIDS BIOTEC ASA (NO) 2004-03-16 US disclosed
WO-2003072657-A1 PROCESS FOR THE PREPARATION OF CATIONIC AZO COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-04 WO disclosed
US-6500410-B1 IMPROVING THE PHOTO SENSITIVITY AND SOLUBILITY OF UV LIGHT PROTECTION FACTOR IN SUN PROTECTING AGENTS COMPRISING INCLUDING WATER SOLUBLE BETA-(1,3) GLUCANS WHICH ARE SUBSTANTIALLY FREE FROM BETA-(1,6) LINKAGES BIOTEC PHARMACON ASA (NO) 2002-12-31 US disclosed
US-6497865-B1 PREPARATIONS CONTAINING WATER SOLUBLE BETA-(1,3) GLUCANS, SUBSTANTIALLY FREE FROM BETA-(1,6) LINKAGES, AND POLYMERS; DECREASES TENDENCY TO FORMING OF STRESS CRACKS BIOTEC PHARMACON ASA (NO) 2002-12-24 US disclosed
US-6497863-B1 PREPARATION COMPRISING WATER SOLUBLE BETA-(1,3) GLUCANS, WHICH ARE SUBSTANTIALLY FREE FROM BETA-(1,6) LINKAGES, ALUMINUM CHLOROHYDRATE, ESTERASE INHIBITORS, AND/OR BACTERICIDAL, RESPECTIVELY BACTERIOSTATIC, AGENTS BIOTEC PHARMACON ASA (NO) 2002-12-24 US disclosed
WO-1999024538-A1 ALKYL POLYGLYCOSIDE ETHER CARBOXYLATES HENKEL CORPORATION (US) 1999-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040255402-A1 Developer components and their use for dyeing keratinic fibers KRT18, DSP, DSG1 TSHR 4883/4885ALDH1A1 903/4885AKR1B1 1045/4885
US-20220040074-A1 Decolorization of Dyed Keratinic Fibers KRT18, CUTA, DSG1 TSHR 4741/4885ALDH1A1 22/4885AKR1B1 353/4885
US-20040170670-A1 Cosmetic sponges CUTA, SUCLG1, AQP3 TSHR 3505/4885ALDH1A1 765/4885AKR1B1 3780/4885
US-20210361544-A1 HYDROGEN PEROXIDE FORMULATIONS IN BARRIER LAYER FILMS WITH A SiOx LAYER KRT18, CUTA, PPOX TSHR 4087/4885ALDH1A1 2633/4885AKR1B1 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.