Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020658 | 1.00 | TSHR (0.31) | TSHRMCHR1HTR2CKCNH2CYP11B2 | |
| SCHEMBL3668331 | 0.90 | TSHR (0.31) | TSHRMCHR1HTR2CKCNH2 | |
| SCHEMBL3670277 | 0.79 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL3028019 | 0.75 | MCHR1 (0.35) | MCHR1HTR2CKCNH2FAAH | |
| SCHEMBL3020655 | 0.73 | MCHR1 (0.34) | MCHR1HTR2CKCNH2PPARA | |
| SCHEMBL3804841 | 0.69 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL589241 | 0.69 | FAAH (0.40) | MCHR1KCNH2FAAH | |
| SCHEMBL3149833 | 0.68 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3840641 | 0.68 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL3013221 | 0.64 | MCHR1 (0.35) | MCHR1HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |