Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666540 | 0.85 | TXNRD1 (0.35) | HTR6KDM4CNR3C1TXNRD1 | |
| SCHEMBL17378828 | 0.84 | HTR6 (0.45) | HTR6KDM4C | |
| SCHEMBL3027641 | 0.83 | KDM4C (0.39) | HTR6KDM4CNR3C1TXNRD1 | |
| SCHEMBL3027646 | 0.83 | KDM4C (0.39) | HTR6KDM4CNR3C1TXNRD1 | |
| SCHEMBL3665118 | 0.81 | POLB (0.34) | HTR6KDM4CTXNRD1 | |
| SCHEMBL3020688 | 0.81 | KDM4C (0.38) | HTR6KDM4C | |
| SCHEMBL17378740 | 0.78 | HTR6 (0.44) | HTR6KDM4C | |
| SCHEMBL17378765 | 0.77 | HTR6 (0.46) | HTR6KDM4C | |
| SCHEMBL3665116 | 0.77 | TXNRD1 (0.34) | TXNRD1 | |
| SCHEMBL17361995 | 0.76 | HTR6 (0.48) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |