Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.34 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027641 | 1.00 | KDM4C (0.39) | KDM4CTXNRD1KDM6BNR3C1HTR6 | |
| SCHEMBL3025404 | 0.87 | KDM4C (0.40) | KDM4CKDM6B | |
| SCHEMBL3666540 | 0.83 | TXNRD1 (0.35) | KDM4CTXNRD1NR3C1HTR6 | |
| SCHEMBL3666543 | 0.83 | HTR6 (0.41) | KDM4CTXNRD1NR3C1HTR6 | |
| SCHEMBL3665118 | 0.79 | POLB (0.34) | KDM4CTXNRD1HTR6 | |
| SCHEMBL3008595 | 0.78 | PLK1 (0.32) | TXNRD1 | |
| SCHEMBL3008602 | 0.78 | PLK1 (0.32) | TXNRD1 | |
| SCHEMBL3665116 | 0.77 | TXNRD1 (0.34) | TXNRD1 | |
| SCHEMBL3020437 | 0.71 | HTR6 (0.43) | KDM4CHTR6 | |
| SCHEMBL3726142 | 0.70 | KDM4C (0.38) | KDM4CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | KDM4C 3322/4885TXNRD1 2457/4885KDM6B 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.