Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367282 | 0.89 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL364801 | 0.85 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL365013 | 0.83 | KDM4E (0.58) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL366405 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL365639 | 0.81 | KMT2A (0.66) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL365212 | 0.81 | KMT2A (0.39) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL366828 | 0.80 | PKM (0.46) | KMT2AALDH1A1PKMRAB9ALMNA | |
| SCHEMBL367733 | 0.79 | KMT2A (0.38) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL367204 | 0.79 | RORC (0.43) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL364206 | 0.78 | KMT2A (0.54) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |