Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367283 | 0.89 | RAB9A (0.44) | PKMALDH1A1KMT2ARAB9AEGFR | |
| SCHEMBL364802 | 0.84 | KDM4E (0.49) | PKMALDH1A1KMT2ARAB9ALMNA | |
| SCHEMBL365014 | 0.82 | KDM4E (0.48) | ALDH1A1KMT2AEGFRGAANPSR1 | |
| SCHEMBL366406 | 0.81 | GABRP (0.41) | PKMALDH1A1KMT2ARAB9AEGFR | |
| SCHEMBL365213 | 0.81 | PKM (0.39) | PKMALDH1A1KMT2ARAB9AEGFR | |
| SCHEMBL366827 | 0.80 | KMT2A (0.45) | PKMALDH1A1KMT2ARAB9ASRC | |
| SCHEMBL365640 | 0.80 | KMT2A (0.43) | PKMALDH1A1KMT2ARAB9AEGFR | |
| SCHEMBL367734 | 0.79 | ATM (0.40) | PKMALDH1A1KMT2ARAB9ANCEH1 | |
| SCHEMBL367205 | 0.77 | EGFR (0.45) | ALDH1A1KMT2AEGFRSRC | |
| SCHEMBL364207 | 0.76 | EGFR (0.47) | ALDH1A1KMT2ARAB9AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |