Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670533 | 0.76 | BIRC5 (0.38) | CYP1A2CYP2C19CYP3A4CYP2C9PDE2A | |
| SCHEMBL4439375 | 0.73 | F11 (0.33) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19785385 | 0.72 | PDE2A (0.47) | CYP1A2CYP2C19CYP3A4PDE2AKDM1A | |
| SCHEMBL6785541 | 0.70 | CTSS (0.38) | PDE2AKDM1AMEN1KMT2ABIRC5 | |
| SCHEMBL6785539 | 0.70 | BIRC5 (0.38) | PDE2AKDM1AMAPTMEN1KMT2A | |
| SCHEMBL3411258 | 0.69 | KDM1A (0.38) | CYP1A2CYP2C19CYP3A4PDE2AKDM1A | |
| SCHEMBL20562388 | 0.69 | MAPT (0.36) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL3410427 | 0.67 | ALDH1A1 (0.35) | CYP1A2CYP2C19CYP3A4MAPTCYP2D6 | |
| SCHEMBL3663442 | 0.67 | MEN1 (0.33) | MAPTMEN1KMT2ANPSR1HTT | |
| SCHEMBL103539 | 0.66 | ACHE (0.37) | MAPTALDH1A1NPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238133-A2 | FUNGICIDAL AMIDES | E. I. du Pont de Nemours and Company (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009094407-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |