Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL1862655 | 0.91 | THRB (0.47) | THRBTSHRTDP1ALDH1A1CYP2D6 | |
| Ether SCHEMBL956738 | 0.90 | THRB (0.46) | THRBTSHRTDP1ALDH1A1MAPT | |
| Ether SCHEMBL173935 | 0.89 | THRB (0.58) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Ether SCHEMBL2865262 | 0.87 | THRB (0.53) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Propylene Glycol SCHEMBL8605999 | 0.86 | TDP1 (0.41) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Propylene Glycol SCHEMBL243614 | 0.86 | TDP1 (0.41) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Ether SCHEMBL2148363 | 0.84 | THRB (0.50) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| 1,3-Butanediol SCHEMBL10562993 | 0.81 | TSHR (0.44) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Propylene Glycol SCHEMBL3669314 | 0.81 | TSHR (0.44) | THRBTSHRTDP1ALDH1A1CYP3A4 | |
| Propylene Glycol SCHEMBL460711 | 0.81 | TDP1 (0.46) | TSHRTDP1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170472-B | Inhibitor combination for lithium salt catalyzed transesterification process and method for removing lithium salt | 陶氏环球技术有限责任公司 | 2020-04-14 | — | — | CN | disclosed |
| US-20180037531-A1 | Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-02-08 | — | — | US | disclosed |
| US-9796650-B2 | Inhibitor combination for lithium salt-catalyzed transesterification process and method for removing lithium salt | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-10-24 | — | — | US | disclosed |
| EP-3087049-A1 | INHIBITOR COMBINATION FOR LITHIUM SALT-CATALYZED TRANSESTERIFICATION PROCESS AND METHOD FOR REMOVING LITHIUM SALT | Dow Global Technologies Llc (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160297736-A1 | Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt | DOW GLOBAL TECHNOLOGIES LLC | 2016-10-13 | — | — | US | disclosed |
| WO-2015099915-A1 | INHIBITOR COMBINATION FOR LITHIUM SALT-CATALYZED TRANSESTERIFICATION PROCESS AND METHOD FOR REMOVING LITHIUM SALT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| EP-2218724-B1 | EPOXY GROUP-CONTAINING ORGANOSILOXANE COMPOUND, CURABLE COMPOSITION FOR TRANSFER MATERIAL, AND FINE PATTERN FORMING METHOD USING THE COMPOSITION | SHOWA DENKO KK (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-8604150-B2 | Epoxy group-containing organosiloxane compound, curable composition for transfer materials and method for forming micropattern using the composition | SHOWA DENKO K.K. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20100258983-A1 | EPOXY GROUP-CONTAINING ORGANOSILOXANE COMPOUND, CURABLE COMPOSITION FOR TRANSFER MATERIALS AND METHOD FOR FORMING MICROPATTERN USING THE COMPOSITION | SHOWA DENKO K.K. (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-2218724-A1 | EPOXY GROUP-CONTAINING ORGANOSILOXANE COMPOUND, CURABLE COMPOSITION FOR TRANSFER MATERIAL, AND FINE PATTERN FORMING METHOD USING THE COMPOSITION | Showa Denko K.K. (JP) | 2010-08-18 | — | — | EP | disclosed |
| WO-2008091114-A1 | PHOTO-CURABLE COMPOSITION HAVING INHERENTLY EXCELLENT RELEASING PROPERTY AND PATTERN TRANSFER PROPERTY, METHOD FOR TRANSFERRING PATTERN USING THE COMPOSITION AND LIGHT RECORDING MEDIUM HAVING POLYMER PATTERN LAYER PRODUCED USING THE COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297736-A1 | Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt | ADH1C, ADH1A, MAP2K1 | THRB 576/4885TSHR 3806/4885TDP1 3776/4885 |
| US-20180037531-A1 | Inhibitor Combination for Lithium Salt-Catalyzed Transesterification Process and Method for Removing Lithium Salt | ADH1C, ADH1A, MAP2K1 | THRB 576/4885TSHR 3806/4885TDP1 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.