SCHEMBL3671487

SCHEMBL3671487

O=S(=O)(c1ccc(Cl)cc1)c1ccc(Oc2cccc(S(=O)(=O)c3ccc(Cl)cc3)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
ALDH1A1 P00352 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
PGR P06401 7/20 0.51
LMNA P02545 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
SOS1 Q07889 1/20 0.45
DAGLA Q9Y4D2 1/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
NR3C1 P04150 1/20 0.45
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853581 0.97 TDP1 (0.53) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL3671281 0.92 PGR (0.57) HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL822945 0.88 ALDH1A1 (0.59) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL4250245 0.86 SRD5A2 (0.47) HTTTDP1L3MBTL1SMN1; SMN2PGR
SCHEMBL10712862 0.86 HTT (0.61) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL3671678 0.86 PGR (0.57) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL10396881 0.86 ALDH1A1 (0.73) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL4374736 0.86 ALDH1A1 (0.73) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL822784 0.86 ALDH1A1 (0.73) HTTTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL809432 0.86 ALDH1A1 (0.73) HTTTDP1L3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed