SCHEMBL3671281

SCHEMBL3671281

O=S(=O)(c1ccc(Oc2cccc(S(=O)(=O)c3cccc(Cl)c3)c2)cc1)c1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 8/20 0.57
HTT P42858 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.50
HSD11B1 P28845 1/20 0.49
FSCN1 Q16658 1/20 0.47
MMP1 P03956 2/20 0.44
MMP13 P45452 2/20 0.44
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP14 P50281 1/20 0.44
SOS1 Q07889 1/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44
ABCC9 O60706 1/20 0.43
ABCC8 Q09428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671678 0.95 PGR (0.57) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL3671487 0.92 HTT (0.58) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL10712862 0.92 HTT (0.61) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL8853581 0.88 TDP1 (0.53) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL10974178 0.84 HSD11B1 (0.61) PGRHTTHSD11B1MMP2MEN1
SCHEMBL3668530 0.82 HTT (0.58) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL1306226 0.82 ALDH1A1 (0.61) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL3669548 0.82 HTT (0.58) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL11418604 0.81 HTT (0.68) PGRHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL2035375 0.81 ALDH1A1 (0.67) PGRHTTSMN1; SMN2HSD11B1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed