SCHEMBL3671678

SCHEMBL3671678

O=S(=O)(c1ccc(Oc2ccc(S(=O)(=O)c3cccc(Cl)c3)cc2)cc1)c1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.57
HTT P42858 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
HSD11B1 P28845 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
ABCC9 O60706 1/20 0.46
ABCC8 Q09428 1/20 0.46
KCNJ11 Q14654 1/20 0.46
KCNJ8 Q15842 1/20 0.46
AKR1B1 P15121 1/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
FSCN1 Q16658 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671281 0.95 PGR (0.57) PGRHTTL3MBTL1TDP1HSD11B1
SCHEMBL10712862 0.89 HTT (0.61) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL10974178 0.89 HSD11B1 (0.61) PGRHTTHSD11B1ALDH1A1MEN1
SCHEMBL3671487 0.86 HTT (0.58) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL29408747 0.85 ALDH1A1 (0.67) PGRHTTHSD11B1SMN1; SMN2ALDH1A1
SCHEMBL2035375 0.85 ALDH1A1 (0.67) PGRHTTHSD11B1SMN1; SMN2ALDH1A1
SCHEMBL2199161 0.84 AKR1B1 (0.56) PGRHSD11B1ALDH1A1MEN1KMT2A
SCHEMBL31435391 0.84 AKR1B1 (0.56) PGRHSD11B1ALDH1A1MEN1KMT2A
SCHEMBL3834491 0.83 HTR6 (0.61) PGRHSD11B1ALDH1A1MEN1KMT2A
SCHEMBL13106033 0.83 PGR (0.46) PGRHTTL3MBTL1TDP1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed