Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37759 | 0.87 | ALDH1A1 (0.38) | MMP2SIGMAR1 | |
| SCHEMBL366500 | 0.86 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL447452 | 0.78 | ALDH1A1 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL339626 | 0.77 | SIGMAR1 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL16597964 | 0.76 | TAAR1 (0.38) | MMP2SIGMAR1 | |
| SCHEMBL819854 | 0.76 | MMP2 (0.38) | MMP2SIGMAR1 | |
| SCHEMBL1312060 | 0.74 | CA12 (0.42) | CHRM2 | |
| Heptane SCHEMBL28860811 | 0.74 | CSNK1E (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4SIGMAR1 | |
| SCHEMBL11658959 | 0.72 | CA12 (0.46) | — | |
| SCHEMBL11654315 | 0.70 | CA12 (0.48) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008970-A1 | HYDROPHOBIC COATING AND METHOD | BRIGHAM YOUNG UNIVERSITY (US) | 2012-01-19 | — | — | WO | claimed |
| US-20110159299-A1 | HYDROPHOBIC COATING AND METHOD | LINFORF MATTEW R | 2011-06-30 | — | — | US | claimed |