Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367390 | 0.90 | AGTR1 (0.34) | EGFRHTR3AMEN1KMT2A | |
| SCHEMBL366075 | 0.87 | MAPT (0.35) | EGFRSRCMEN1KMT2A | |
| SCHEMBL366116 | 0.78 | CA1 (0.41) | EGFR | |
| SCHEMBL365226 | 0.77 | ATM (0.37) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL365264 | 0.75 | EPHX1 (0.45) | MEN1KMT2ANPC1 | |
| SCHEMBL365256 | 0.75 | EGFR (0.40) | EGFRSRCMEN1KMT2ANPC1 | |
| SCHEMBL367244 | 0.74 | KDM4E (0.33) | MEN1KMT2A | |
| SCHEMBL367222 | 0.74 | EGFR (0.41) | EGFRSRCHTR2AHTR2CNPC1 | |
| SCHEMBL366567 | 0.74 | PSEN1 (0.38) | EGFRSRCMEN1KMT2A | |
| SCHEMBL365771 | 0.72 | EGFR (0.43) | EGFRSRCHTR2AHTR2CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |