Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365213 | 0.90 | PKM (0.39) | EGFRSRCNCEH1RAB9APKM | |
| SCHEMBL367616 | 0.88 | NCEH1 (0.46) | EGFRSRCNCEH1RAB9APKM | |
| SCHEMBL365490 | 0.87 | NCEH1 (0.39) | EGFRSRCNCEH1RAB9APKM | |
| SCHEMBL367283 | 0.81 | RAB9A (0.44) | EGFRSRCNCEH1RAB9APKM | |
| SCHEMBL366612 | 0.80 | ACHE (0.38) | NCEH1KMT2AACHE | |
| SCHEMBL365837 | 0.80 | CNR2 (0.37) | RAB9AKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL366567 | 0.79 | PSEN1 (0.38) | EGFRSRCKMT2AALDH1A1TSHR | |
| SCHEMBL366481 | 0.79 | ACHE (0.39) | RAB9AACHENPC1 | |
| SCHEMBL365264 | 0.78 | EPHX1 (0.45) | RAB9AKMT2AMAOBNPC1TSHR | |
| SCHEMBL365771 | 0.77 | EGFR (0.43) | EGFRSRCKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |