Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367245 | 0.90 | EGFR (0.33) | HTR3AEGFRMEN1KMT2A | |
| SCHEMBL365226 | 0.86 | ATM (0.37) | AGTR1HRH2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL366116 | 0.86 | CA1 (0.41) | AGTR1EGFR | |
| SCHEMBL366075 | 0.77 | MAPT (0.35) | EGFRALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL367409 | 0.74 | EPHX1 (0.48) | ALDH1A1SMN1; SMN2TSHRKDM4EMEN1 | |
| SCHEMBL365213 | 0.74 | PKM (0.39) | EGFRALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL367389 | 0.74 | IDO1 (0.36) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL367671 | 0.73 | PSEN1 (0.39) | AGTR1EGFRALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL366020 | 0.73 | STS (0.41) | AGTR1EGFRALDH1A1L3MBTL1MAPT | |
| SCHEMBL366821 | 0.73 | AGTR1 (0.41) | AGTR1EGFRALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |