Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | STS | P08842 | 8/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367390 | 0.86 | AGTR1 (0.34) | EGFRAGTR1 | |
| SCHEMBL366020 | 0.86 | STS (0.41) | CA1CA2CA9STSEGFR | |
| SCHEMBL365213 | 0.80 | PKM (0.39) | EGFR | |
| SCHEMBL367671 | 0.79 | PSEN1 (0.39) | EGFRAGTR1 | |
| SCHEMBL366821 | 0.79 | AGTR1 (0.41) | CA1CA2CA9EGFRAGTR1 | |
| SCHEMBL367245 | 0.78 | EGFR (0.33) | EGFR | |
| SCHEMBL367256 | 0.78 | EGFR (0.40) | EGFRAGTR1 | |
| SCHEMBL365789 | 0.76 | EGFR (0.41) | EGFRAGTR1 | |
| SCHEMBL367409 | 0.75 | EPHX1 (0.48) | — | |
| SCHEMBL365023 | 0.73 | EGFR (0.40) | EGFRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |