Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11572419 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| Hydrochloric Acid SCHEMBL11572407 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| Butane SCHEMBL27520586 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL27678592 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| Hydrochloric Acid SCHEMBL9619305 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| Bromide SCHEMBL25216737 | 0.98 | LTA4H (0.36) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL3445934 | 0.93 | LTA4H (0.38) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL3411655 | 0.92 | LTA4H (0.33) | LTA4HPCSK9PTGS2CES2CES1 | |
| SCHEMBL5389878 | 0.91 | DNM1 (0.40) | LTA4HPTGS2CES2CES1SMN1; SMN2 | |
| SCHEMBL5394695 | 0.91 | DNM1 (0.40) | LTA4HPTGS2CES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805430-A | Preparation method of seleno-phosphide and thiophosphite | 烟台大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114573422-A | Treatment method of 3-methyl-3-butene-1-ol process waste liquid | 万华化学集团股份有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-110041373-A | The recovery method of noble metal catalyst in a kind of production procedure of centre Lei Dipawei | 江苏万年长药业有限公司 | 2019-07-23 | — | — | CN | claimed |
| EP-3484840-A1 | CATALYTIC PROCESS FOR DIENE DIMERIZATION | Total Raffinage Chimie (FR) | 2019-05-22 | — | — | EP | claimed |
| WO-2018011157-A1 | CATALYTIC PROCESS FOR DIENE DIMERIZATION | TOTAL RAFFINAGE CHIMIE (FR) | 2018-01-18 | — | — | WO | claimed |
| US-7816525-B1 | Process for the preparation of optically pure tetrahydropterins and derivatives, and specifically of optically pure tetrahydrofolic acid and derivatives thereof, by stereospecific hydrogenation | Merck & Cie (CH) | 2010-10-19 | — | — | US | claimed |
| US-20080306263-A1 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation | MULLER HANS RUDOLF | 2008-12-11 | — | — | US | claimed |
| CN-1264842-C | Process for the preparation of optically pure tetrahydropterin and derivatives thereof, in particular optically pure tetrahydrofolic acid and derivatives thereof, by stereoselective hydrogenation | EPROVA AG (CH) | 2006-07-19 | — | — | CN | claimed |
| EP-1622861-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2006-02-08 | — | — | EP | claimed |
| WO-2004101496-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2004-11-25 | — | — | WO | claimed |
| WO-2001042197-A1 | METHOD FOR PREPARING A POLYAROMATIC COMPOUND | RHODIA CHIMIE (FR) | 2001-06-14 | — | — | WO | claimed |
| EP-0975571-A1 | METHOD FOR PREPARING AROMATIC ALDEHYDES | RHODIA CHIMIE (FR) | 2000-02-02 | — | — | EP | claimed |
| WO-1999042424-A1 | METHOD FOR PREPARING AROMATIC KETONE COMPOUNDS | RHODIA CHIMIE (FR) | 1999-08-26 | — | — | WO | claimed |
| WO-1998047848-A1 | METHOD FOR PREPARING AROMATIC ALDEHYDES | RHODIA CHIMIE (FR) | 1998-10-29 | — | — | WO | claimed |
| EP-0249984-B1 | PROCESS FOR PRODUCING BUTENE-1 POLYMER | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1992-01-08 | — | — | EP | claimed |
| JP-1060623-A | — | — | None | — | — | JP | disclosed |
| CN-115210213-B | Active ester, curable resin composition, and cured product | DIC株式会社 | 2024-12-10 | — | — | CN | disclosed |
| US-4119652-A | HYDROGENATION CATALYSTS; COORDINATION COMPOUNDS OF IRIDIUM, RHODIUM OR RUTHENIUM WITH PHOSPHINE OR ARSINE LIGANDS; OPTICALLY ACTIVE | MONSANTO COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
| US-3968147-A | COORDINATION CATALYST | MONSANTO COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306263-A1 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation | DHFR, MTHFD2, MTHFD1 | LTA4H 1467/4885PCSK9 943/4885PTGS2 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.