Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9244909 | 0.98 | LTA4H (0.37) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5405337 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5397657 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5388357 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5389878 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| Hydrochloric Acid SCHEMBL25201413 | 0.98 | LTA4H (0.37) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5393997 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL5394695 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL18660546 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 | |
| SCHEMBL27793173 | 0.98 | DNM1 (0.40) | LTA4HSIGMAR1CES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372209-A | Synthesis method of megastigmatrienone | 上海烟草集团有限责任公司 | 2021-09-10 | — | — | CN | claimed |
| US-7816525-B1 | Process for the preparation of optically pure tetrahydropterins and derivatives, and specifically of optically pure tetrahydrofolic acid and derivatives thereof, by stereospecific hydrogenation | Merck & Cie (CH) | 2010-10-19 | — | — | US | claimed |
| US-20080306263-A1 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation | MULLER HANS RUDOLF | 2008-12-11 | — | — | US | claimed |
| CN-1264842-C | Process for the preparation of optically pure tetrahydropterin and derivatives thereof, in particular optically pure tetrahydrofolic acid and derivatives thereof, by stereoselective hydrogenation | EPROVA AG (CH) | 2006-07-19 | — | — | CN | claimed |
| CN-113372209-B | Synthesis method of megastigmatrienone | 上海烟草集团有限责任公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113372209-A | Synthesis method of megastigmatrienone | 上海烟草集团有限责任公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-109320718-A | A kind of high barrier transparent flexible display material and preparation method thereof | 中国科学院长春应用化学研究所 | 2019-02-12 | — | — | CN | disclosed |
| CN-105754099-B | Composition and polymer | 旭化成株式会社 | 2018-09-18 | — | — | CN | disclosed |
| CN-104271618-B | Preparation of functional polymers using phosphide initiators | 株式会社普利司通 | 2017-05-17 | — | — | CN | disclosed |
| EP-2831128-B1 | PREPARATION OF FUNCTIONAL POLYMERS USING PHOSPHIDE INITIATORS | BRIDGESTONE CORP (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-9163104-B2 | Preparation of functional polymers using phosphide initiators | BRIDGESTONE CORPORATION (JP) | 2015-10-20 | — | — | US | disclosed |
| US-20150065673-A1 | Preparation Of Functional Polymers Using Phosphide Initiators | BRIDGESTONE CORPORATION (JP) | 2015-03-05 | — | — | US | disclosed |
| US-20080306263-A1 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation | MULLER HANS RUDOLF | 2008-12-11 | — | — | US | disclosed |
| US-20080279809-A1 | COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES | HENKEL AG & CO. KGAA (DE) | 2008-11-13 | — | — | US | disclosed |
| US-7214747-B2 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-10-27 | — | — | US | disclosed |
| EP-1200437-B1 | METHOD FOR PRODUCING BY STEREOSPECIFIC HYDRATION TETRAHYDROPTERINS AND OPTICALLY PURE DERIVATIVES, IN PARTICULAR TETRAHYDROFOLIC ACID AND ITS OPTICALLY PURE DERIVATIVES | EPROVA AG (CH) | 2004-03-10 | — | — | EP | disclosed |
| EP-1200437-A1 | METHOD FOR PRODUCING BY STEREOSPECIFIC HYDRATION TETRAHYDROPTERINS AND OPTICALLY PURE DERIVATIVES, IN PARTICULAR TETRAHYDROFOLIC ACID AND ITS OPTICALLY PURE DERIVATIVES | EPROVA AG Forschungsinstitut (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004120-A1 | METHOD FOR PRODUCING BY STEREOSPECIFIC HYDRATION TETRAHYDROPTERINS AND OPTICALLY PURE DERIVATIVES, IN PARTICULAR TETRAHYDROFOLIC ACID AND ITS OPTICALLY PURE DERIVATIVES | EPROVA AG (CH) | 2001-01-18 | — | — | WO | disclosed |
| US-4301318-A | OBTAINED BY REACTING ETHYLENE USING A NICKEL YLIDE CATALYST; SOLVENT EXTRACTION OF CATALYST USING AMMONIUM HYDROXIDE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279809-A1 | COATING MATERIAL FOR METAL SURFACES HAVING ANTIADHESIVE PROPERTIES | ZKSCAN2, CAD, ZRANB2 | LTA4H 1284/4885SIGMAR1 686/4885CES2 1809/4885 |
| US-20080306263-A1 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation | DHFR, MTHFD2, MTHFD1 | LTA4H 1467/4885SIGMAR1 4170/4885CES2 4126/4885 |
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | CCRL2, ARL1, OSBP2 | LTA4H 3423/4885SIGMAR1 626/4885CES2 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.