Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366828 | 0.89 | PKM (0.46) | RAB9AEGFRSRCPKMALDH1A1 | |
| SCHEMBL364802 | 0.83 | KDM4E (0.49) | RAB9APKMALDH1A1KMT2ALMNA | |
| SCHEMBL364594 | 0.83 | EGFR (0.44) | EGFRSRCALDH1A1KMT2ALMNA | |
| SCHEMBL365256 | 0.81 | EGFR (0.40) | RAB9AEGFRSRCPKMALDH1A1 | |
| SCHEMBL367282 | 0.81 | KMT2A (0.47) | RAB9AEGFRSRCPKMALDH1A1 | |
| SCHEMBL366406 | 0.80 | GABRP (0.41) | RAB9AEGFRSRCPKMALDH1A1 | |
| SCHEMBL365490 | 0.79 | NCEH1 (0.39) | RAB9AEGFRSRCPKMKMT2A | |
| SCHEMBL365640 | 0.79 | KMT2A (0.43) | RAB9AEGFRSRCPKMALDH1A1 | |
| SCHEMBL366032 | 0.77 | PSEN1 (0.38) | EGFRSRCALDH1A1KMT2ALMNA | |
| SCHEMBL365101 | 0.75 | KMT2A (0.51) | RAB9AKMT2ATSHRNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |