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SCHEMBL3672964

SCHEMBL3672964

Cn1nc(C(F)(F)F)cc1Oc1cc(Cl)cc(Oc2cc(C(F)(F)F)n(C)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.46
▸ MAPT P10636 2/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ TGFBR1 P36897 5/20 0.41
▸ PKM P14618 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ ADORA2A P29274 1/20 0.38
▸ ADORA1 P30542 1/20 0.38
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.35
▸ PTGS1 P23219 3/20 0.33
▸ PTGS2 P35354 3/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ THPO P40225 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29981407 1.00 KMT2A (0.46) KMT2AMAPTNPSR1SMN1; SMN2TGFBR1
SCHEMBL5226326 0.90 KMT2A (0.43) KMT2AMAPTNPSR1SMN1; SMN2TGFBR1
SCHEMBL29980924 0.88 KMT2A (0.41) KMT2AMAPTNPSR1SMN1; SMN2TGFBR1
SCHEMBL3678419 0.88 KMT2A (0.41) KMT2AMAPTNPSR1SMN1; SMN2TGFBR1
SCHEMBL3672424 0.78 KMT2A (0.39) KMT2ATGFBR1PKMADORA2AADORA1
SCHEMBL5223851 0.76 MAPT (0.45) KMT2AMAPTNPSR1SMN1; SMN2PKM
SCHEMBL12819416 0.76 KMT2A (0.51) KMT2ANPSR1TGFBR1ADORA2AADORA1
SCHEMBL6281244 0.74 ADORA2A (0.50) KMT2AMAPTTGFBR1PKMADORA2A
SCHEMBL5227796 0.74 KMT2A (0.51) KMT2ATGFBR1ADORA2AADORA1NPC1
SCHEMBL3385215 0.73 TGFBR1 (0.38) KMT2AMAPTNPSR1SMN1; SMN2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4094580-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL) ARYL CARBOXYLIC ACID AMIDES Bayer CropScience Aktiengesellschaft (DE) 2022-11-30 — — EP claimed
US-10159249-B2 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-12-25 — — US claimed
EP-2854538-B1 HERBICIDE COMPOSITIONS CONTAINING N-(TETRAZOL-5-YL)ARYL CARBOXYLIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2017-05-03 — — EP claimed
US-20170027174-A1 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides BAYER CROSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-02 — — US claimed
EP-3073828-A2 USE OF 2-CHLORO-3-(METHYLSULFANYL)-N-(1-METHYL-1H-TETRAZOL-5-YL)-4-(TRIFLUOROMETHYL)BENZAMIDE OR ITS SALTS FOR CONTROLLING UNWANTED PLANTS IN AREAS OF TRANSGENIC CROP PLANTS BEING TOLERANT TO HPPD INHIBITOR HERBICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-10-05 — — EP claimed
EP-3060057-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)-ARYL CARBOXYLIC ACID AMIDES Bayer CropScience Aktiengesellschaft (DE) 2016-08-31 — — EP claimed
US-20160242419-A1 Herbicidal Compositions Containing N-(1,3,4-oxadiazol-2-yl)-aryl Carboxylic Acid Amides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-25 — — US claimed
US-20150264933-A1 HERBICIDAL COMPOSITIONS COMPRISING N-TETRAZOL-5-YL)- OR N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2015-09-24 — — US claimed
EP-2921052-A1 HERBICIDE COMPOUNDS CONTAINING N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYL CARBOXYLIC ACID AMIDES Bayer CropScience AG (DE) 2015-09-23 — — EP claimed
WO-2015078828-A2 USE OF 2-CHLORO-3-(METHYLSULFANYL)-N-(1-METHYL-1H-TETRAZOL-5-YL)-4-(TRIFLUOROMETHYL)BENZAMIDE OR ITS SALTS FOR CONTROLLING UNWANTED PLANTS IN AREAS OF TRANSGENIC CROP PLANTS BEING TOLERANT TO HPPD INHIBITOR HERBICIDES BAYER CROPSCIENCE AG (DE) 2015-06-04 — — WO claimed
WO-2015059187-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL)-ARYL CARBOXYLIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2015-04-30 — — WO claimed
EP-2854538-A1 HERBICIDAL COMPOSITIONS COMPRISING N-(TETRAZOL-5-YL)- OR N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES Bayer CropScience AG (DE) 2015-04-08 — — EP claimed
WO-2013174845-A1 HERBICIDAL COMPOSITIONS COMPRISING N-(TETRAZOL-5-YL)- OR N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2013-11-28 — — WO claimed
US-20100323894-A1 HERBICIDAL COMBINATION BAYER CROPSCIENCE AG (DE) 2010-12-23 — — US claimed
EP-2052615-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 — — EP claimed
EP-4094580-A1 HERBICIDAL COMPOSITIONS CONTAINING N-(1,3,4-OXADIAZOL-2-YL) ARYL CARBOXYLIC ACID AMIDES Bayer CropScience Aktiengesellschaft (DE) 2022-11-30 — — EP disclosed
CN-105658067-B Herbicidal compositions containing N- (1,3, 4-oxadiazol-2-yl) -aryl carboxylic acid amides 拜耳作物科学股份公司 2020-07-31 — — CN disclosed
WO-2009053054-A2 HERBICIDAL COMBINATION BAYER CROPSCIENCE AG (DE) 2009-04-30 — — WO disclosed
EP-2052615-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 — — EP disclosed
EP-2052615-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150264933-A1 HERBICIDAL COMPOSITIONS COMPRISING N-TETRAZOL-5-YL)- OR N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES HDHD5, AADAC, DDT KMT2A 881/4885MAPT 2622/4885NPSR1 3966/4885
US-20170027174-A1 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides HPD, PGD, TKT KMT2A 8/4885MAPT 3732/4885NPSR1 3856/4885
US-20160242419-A1 Herbicidal Compositions Containing N-(1,3,4-oxadiazol-2-yl)-aryl Carboxylic Acid Amides AADAC, DDT, DNPH1 KMT2A 932/4885MAPT 3824/4885NPSR1 3752/4885
US-10159249-B2 Use of 2-chloro-3-(methylsulfanyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide or its salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides HPD, PGD, PHYKPL KMT2A 10/4885MAPT 3773/4885NPSR1 4001/4885
US-20100323894-A1 HERBICIDAL COMBINATION DDT, CYP4B1, CYP1B1 KMT2A 259/4885MAPT 4445/4885NPSR1 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.