Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058986 | 0.95 | HTT (0.56) | HTTL3MBTL1TDP1SMN1; SMN2POLB | |
| SCHEMBL3668530 | 0.86 | HTT (0.58) | HTTL3MBTL1TDP1SMN1; SMN2POLB | |
| SCHEMBL30084552 | 0.84 | LMNA (0.54) | HTTSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL3677379 | 0.84 | LMNA (0.54) | HTTSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL9756893 | 0.83 | HTR6 (0.48) | HTTL3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3839132 | 0.83 | HTR6 (0.61) | HTTSMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL11418604 | 0.81 | HTT (0.68) | HTTL3MBTL1TDP1SMN1; SMN2POLB | |
| SCHEMBL3669592 | 0.81 | HTT (0.55) | HTTL3MBTL1TDP1SMN1; SMN2POLB | |
| SCHEMBL20389273 | 0.80 | HTR6 (0.59) | HTTTDP1ALDH1A1PKMLMNA | |
| SCHEMBL3671678 | 0.79 | PGR (0.57) | HTTL3MBTL1TDP1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329444-B1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-1138712-B1 | Polyarylene copolymers and proton-conductive membrane | JSR CORP (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6933068-B2 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) | 2005-08-23 | — | — | US | disclosed |
| US-6833426-B2 | A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer | JSR CORPORATION (JP) | 2004-12-21 | — | — | US | disclosed |
| US-6812290-B2 | FOR USE AS ELECTROLYTES | JSR CORPORATION (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030195301-A1 | Polyarylene copolymers and proton-conductive membrane | JSR CORPORATION (JP) | 2003-10-16 | — | — | US | disclosed |
| US-20030173547-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1329444-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR Corporation (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6555626-B2 | Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity | JSR CORPORATION (JP) | 2003-04-29 | — | — | US | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |
| US-20010037000-A1 | Polyarylene copolymers and proton-conductive membrane | JSR CORPORATION (JP) | 2001-11-01 | — | — | US | disclosed |
| EP-1138712-A2 | Polyarylene copolymers and proton-conductive membrane | JSR Corporation (JP) | 2001-10-04 | — | — | EP | disclosed |