SCHEMBL3668530

SCHEMBL3668530

O=S(=O)(c1ccc(I)cc1)c1ccc(Oc2cccc(S(=O)(=O)c3ccc(I)cc3)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.51
PGR P06401 5/20 0.44
SOS1 Q07889 1/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
RAPGEF4 Q8WZA2 1/20 0.40
PKM P14618 1/20 0.40
MTNR1B P49286 1/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6058986 0.92 HTT (0.56) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3673494 0.86 HTT (0.53) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3669592 0.86 HTT (0.55) HTTL3MBTL1TDP1SMN1; SMN2SOS1
SCHEMBL1306226 0.83 ALDH1A1 (0.61) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3671487 0.83 HTT (0.58) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3669548 0.83 HTT (0.58) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL11418604 0.82 HTT (0.68) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL9779108 0.82 HTT (0.56) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3671281 0.82 PGR (0.57) HTTL3MBTL1TDP1SMN1; SMN2PGR
SCHEMBL3675283 0.82 PGR (0.57) HTTL3MBTL1TDP1SMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed