SCHEMBL3669592

SCHEMBL3669592

O=S(=O)(c1ccc(I)cc1)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(I)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 7/20 0.55
SMN1; SMN2 Q16637 6/20 0.55
MMP2 P08253 2/20 0.53
MMP9 P14780 2/20 0.53
ALDH1A1 P00352 4/20 0.52
PKM P14618 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 1/20 0.48
LMNA P02545 4/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
XBP1 P17861 1/20 0.47
MAPK1 P28482 1/20 0.47
MDM2 Q00987 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23870583 0.90 HTT (0.71) HTTSMN1; SMN2MMP2MMP9ALDH1A1
SCHEMBL3668530 0.86 HTT (0.58) HTTSMN1; SMN2MMP2MMP9ALDH1A1
SCHEMBL896933 0.85 RAPGEF4 (0.56) MMP2MMP9ALDH1A1PKMCA1
SCHEMBL1133770 0.83 MMP2 (0.50) HTTSMN1; SMN2MMP2MMP9ALDH1A1
SCHEMBL25564566 0.83 MMP2 (0.50) HTTSMN1; SMN2MMP2MMP9ALDH1A1
SCHEMBL21763724 0.83 PKM (0.79) HTTMMP2MMP9ALDH1A1PKM
SCHEMBL3673494 0.81 HTT (0.53) HTTSMN1; SMN2MMP2MMP9ALDH1A1
SCHEMBL3841043 0.80 LTA4H (0.50) MMP2MMP9ALDH1A1TDP1CA1
SCHEMBL3845620 0.80 LTA4H (0.50) MMP2MMP9ALDH1A1TDP1CA1
SCHEMBL2883028 0.80 LTA4H (0.50) MMP2MMP9ALDH1A1TDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed