Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305303 | 1.00 | ALDH1A1 (0.67) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL27313043 | 0.86 | ALDH1A1 (0.58) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL9272191 | 0.85 | MAPT (0.53) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL30234471 | 0.85 | MAPT (0.53) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL11365960 | 0.83 | GPR84 (0.51) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL7382969 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ATMGPR84MAPK1NUDT1 | |
| SCHEMBL9795027 | 0.82 | NUDT1 (0.61) | ALDH1A1ATMMAPK1BCAT2NUDT1 | |
| SCHEMBL29822224 | 0.82 | NUDT1 (0.61) | ALDH1A1ATMMAPK1BCAT2NUDT1 | |
| SCHEMBL30344211 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ATMGPR84MAPK1PBRM1 | |
| SCHEMBL117198 | 0.80 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84MAPK1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2183217-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2010-05-12 | — | — | EP | disclosed |
| CN-101541748-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2009-09-23 | — | — | CN | disclosed |
| WO-2009015067-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-29 | — | — | WO | disclosed |
| CN-101027051-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1099413-C | Certain fused pyrrolecarboxanilides, new class of gaba brain receptor ligands | NEUROGEN CORP (US) | 2003-01-22 | — | — | CN | disclosed |
| EP-0785789-B1 | DIAZEPINO-INDOLES AS PHOSPHODIESTERASE IV INHIBITORS | PFIZER (FR) | 2002-09-11 | — | — | EP | disclosed |
| CN-1143953-A | Certain fused pyrrolecarboxanilides, new class of gaba brain receptor ligands | NEUROGEN CORP (US) | 1997-02-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | NR3C1, MC2R, NR3C2 | ALDH1A1 4038/4885ATM 3429/4885GPR84 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.