Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643157 | 0.80 | ACHE (0.45) | POLLDRD2DRD3HTR1AHTR7 | |
| SCHEMBL3642763 | 0.80 | PDPK1 (0.49) | DRD2DRD3KDM1AMAOAMAOB | |
| SCHEMBL3642761 | 0.78 | ADRA2A (0.42) | DRD2DRD3HTR1ASYK | |
| SCHEMBL3674201 | 0.78 | MTNR1A (0.38) | POLLDRD2DRD3HTR1AHTR7 | |
| SCHEMBL3642023 | 0.72 | GRIA1 (0.44) | DRD2DRD3KDM1AMAOAMAOB | |
| SCHEMBL3644416 | 0.72 | GRIA1 (0.44) | DRD2DRD3HTR1ACHRM2CHRM1 | |
| SCHEMBL3642020 | 0.71 | GRIA1 (0.44) | HTR1A | |
| SCHEMBL13959050 | 0.70 | ACHE (0.43) | DRD2DRD3KDM1AMAOAMAOB | |
| SCHEMBL30865706 | 0.67 | HTR1A (0.58) | ARHTR1AHTR7 | |
| SCHEMBL3644469 | 0.66 | IMPDH2 (0.46) | DRD2DRD3HTR7CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173712-A2 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-04-14 | — | — | EP | claimed |
| WO-2009003719-A2 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-01-08 | — | — | WO | claimed |