SCHEMBL3675720

SCHEMBL3675720

CO[CH]c1cccc(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.62
RELA Q04206 1/20 0.60
NFE2L2 Q16236 4/20 0.56
CYP19A1 P11511 1/20 0.55
NQO2 P16083 1/20 0.55
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53
TUBB4B P68371 1/20 0.53
TUBB3 Q13509 1/20 0.53
TUBB2A Q13885 1/20 0.53
TUBB8 Q3ZCM7 1/20 0.53
TUBA3E Q6PEY2 1/20 0.53
TUBA1A Q71U36 1/20 0.53
TUBA1C Q9BQE3 1/20 0.53
TUBB6 Q9BUF5 1/20 0.53
TUBB2B Q9BVA1 1/20 0.53
TUBB1 Q9H4B7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23158820 0.82 RELA (0.84) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL31317665 0.82 RELA (0.84) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL700056 0.82 RELA (0.84) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL2099510 0.82 CHRM5 (0.67) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL700055 0.82 RELA (0.84) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL10570523 0.82 TLR4 (0.50) CHRM5
SCHEMBL28816966 0.80 CHRM5 (0.55) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL97058 0.80 CHRM5 (0.64) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL28206170 0.79 RELA (0.67) CHRM5RELANFE2L2CYP19A1NQO2
SCHEMBL6204379 0.79 CHRM5 (0.53) CHRM5RELANFE2L2CYP19A1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-117098670-A Thermosensitive recording medium 日本制纸株式会社 2023-11-21 CN disclosed
CN-117042978-A Thermosensitive recording medium 日本制纸株式会社 2023-11-10 CN disclosed
CN-114786957-B Thermosensitive recording medium 日本制纸株式会社 2023-08-29 CN disclosed
CN-114502389-B Thermosensitive recording medium 日本制纸株式会社 2023-07-14 CN disclosed
CN-115210082-A Thermosensitive recording medium 日本制纸株式会社 2022-10-18 CN disclosed
CN-114786957-A Thermosensitive recording medium 日本制纸株式会社 2022-07-22 CN disclosed
CN-114502389-A Thermosensitive recording medium 日本制纸株式会社 2022-05-13 CN disclosed
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 EP disclosed
US-8710089-B2 Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2014-04-29 US disclosed
US-20100331343-A1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2010-12-30 US disclosed
US-7829724-B2 Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2010-11-09 US disclosed
US-20090042905-A1 TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AETERNA ZENTARIS GMBH (DE) 2009-02-12 US disclosed
CN-101272782-A Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH (DE) 2008-09-24 CN disclosed
WO-2008098977-A1 NOVEL TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2008-08-21 WO disclosed
EP-1958631-A1 Novel triazole derivatives as ligands of G-protein coupled receptors AEterna Zentaris GmbH (DE) 2008-08-20 EP disclosed
EP-1915149-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AEterna Zentaris GmbH (DE) 2008-04-30 EP disclosed
US-20070208061-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2007-09-06 US disclosed
WO-2007020013-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2007-02-22 WO disclosed
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208061-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS GIPR, GHSR, GPR119 CHRM5 1729/4885RELA 2281/4885NFE2L2 3246/4885
US-20100331343-A1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS GIPR, GHSR, GPR119 CHRM5 1729/4885RELA 2281/4885NFE2L2 3246/4885
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors GIPR, GHSR, GPR119 CHRM5 1729/4885RELA 2281/4885NFE2L2 3246/4885
US-20090042905-A1 TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS GPR3, GRK3, GPR88 CHRM5 740/4885RELA 4032/4885NFE2L2 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.