Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158820 | 0.84 | RELA (0.84) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL700056 | 0.84 | RELA (0.84) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL2099510 | 0.84 | CHRM5 (0.67) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL700055 | 0.84 | RELA (0.84) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL31317665 | 0.84 | RELA (0.84) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL471006 | 0.83 | RELA (0.69) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL7194475 | 0.83 | RELA (0.69) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL257114 | 0.83 | RELA (0.69) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL6615780 | 0.80 | CHRM5 (0.62) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL7684603 | 0.80 | NPC1 (0.65) | CHRM5RELANFE2L2CYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563943-A | Bio-based polymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2019-12-13 | — | — | CN | claimed |
| US-10201527-B2 | Benzimidazole derivatives: preparation and pharmaceutical applications | MEI PHARMA, INC. (US) | 2019-02-12 | — | — | US | claimed |
| EP-3050871-B1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR) | 2018-11-07 | — | — | EP | claimed |
| EP-1915149-B1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2018-10-10 | — | — | EP | claimed |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-04 | — | — | US | claimed |
| US-10064843-B2 | Bis-amide derivative and use thereof | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2018-09-04 | — | — | US | claimed |
| CN-105906486-B | The synthetic method of Sarpogrelate intermediate 2 [2 (3 methoxyphenyl) ethyl] phenol | 安徽修制药有限公司 | 2018-04-20 | — | — | CN | claimed |
| US-20170360757-A1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD. (SG) | 2017-12-21 | — | — | US | claimed |
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | claimed |
| US-20160297751-A1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2016-10-13 | — | — | US | claimed |
| US-6583179-B2 | For therapy of uterine fibroids, endometriosis, polycystic ovarian disease, dysfunctional uterine bleeding, breast cancer and ovarian cancer; depletion of oocytes; spermatocyte depletion; for female and male contraception | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-06-24 | — | — | US | claimed |
| EP-1313713-A2 | 4-PYRIMIDINAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-05-28 | — | — | EP | claimed |
| US-20030008883-A1 | 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-01-09 | — | — | US | claimed |
| US-6359144-B1 | BIOSYNTHESIS; SCREENING | LION BIOSCIENCE AG (DE) | 2002-03-19 | — | — | US | claimed |
| WO-2002012198-A2 | 4-PYRIMIDINAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-02-14 | — | — | WO | claimed |
| WO-1999059409-A1 | COMPOUNDS AND USES THEREOF | MATSUMOTO RAE R (US) | 1999-11-25 | — | — | WO | claimed |
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0264908-B1 | High sensitivity resists having autodecomposition temperatures greater than about 160 C | IBM (US) | 1996-03-20 | — | — | EP | claimed |
| US-4931379-A | ADDITION POLYMERS HAVING PENDANT ACID-LABILE GROUPS, E.G CARBONATES, AND SIDECHAINS FOR ADDED STABILITY; SEMICONDUCTORS; MICROLITHOGRAPHY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1990-06-05 | — | — | US | claimed |
| EP-0264908-A2 | High sensitivity resists having autodecomposition temperatures greater than about 160 C | International Business Machines Corporation (US) | 1988-04-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10201527-B2 | Benzimidazole derivatives: preparation and pharmaceutical applications | HDAC5, HDAC1, HDAC8 | CHRM5 4518/4885RELA 1549/4885NFE2L2 1568/4885 |
| US-20030008883-A1 | 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods | CASP3, CASP5, CASP4 | CHRM5 1987/4885RELA 3486/4885NFE2L2 1081/4885 |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | SQOR, DHPS, QDPR | CHRM5 3909/4885RELA 1484/4885NFE2L2 233/4885 |
| US-10064843-B2 | Bis-amide derivative and use thereof | CYP2C8, CYP4F8, CYP2F1 | CHRM5 4651/4885RELA 1302/4885NFE2L2 2686/4885 |
| US-20160297751-A1 | NOVEL BIS-AMIDE DERIVATIVE AND USE THEREOF | CYP2C8, CYP4F8, CYP2F1 | CHRM5 4644/4885RELA 1352/4885NFE2L2 2505/4885 |
| US-20170360757-A1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | HDAC5, HDAC1, HDAC8 | CHRM5 4518/4885RELA 1549/4885NFE2L2 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.