Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365469 | 0.88 | PLA2G2A (0.39) | ALDH1A1HPGDPLA2G2A | |
| SCHEMBL366239 | 0.86 | PLA2G2A (0.41) | ALDH1A1HPGDPLA2G2ACNR2 | |
| SCHEMBL366442 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDCNR1CNR2 | |
| SCHEMBL366186 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HPGDPLA2G2ACNR2 | |
| SCHEMBL364389 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HPGD | |
| SCHEMBL367569 | 0.82 | SRC (0.46) | ALDH1A1HPGD | |
| SCHEMBL366838 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDPLA2G2ACNR2 | |
| SCHEMBL367618 | 0.81 | BAZ2B (0.38) | ALDH1A1HPGDPLA2G2A | |
| SCHEMBL366876 | 0.80 | EGFR (0.44) | ALDH1A1HPGD | |
| SCHEMBL367330 | 0.79 | EGFR (0.46) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |