Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682999 | 0.71 | ERN1 (0.35) | MEN1KMT2A | |
| SCHEMBL3723397 | 0.71 | ALDH1A1 (0.33) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL3682112 | 0.71 | ESR1 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3682703 | 0.70 | NPC1 (0.37) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL3680426 | 0.70 | MMP3 (0.41) | MAPTRAB9AMEN1KMT2AGAA | |
| SCHEMBL3642382 | 0.68 | P2RX3 (0.34) | RAB9ANPC1 | |
| SCHEMBL3689515 | 0.68 | BRD4 (0.43) | — | |
| SCHEMBL3646252 | 0.67 | L3MBTL1 (0.36) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3676121 | 0.66 | ESR2 (0.36) | GAA | |
| SCHEMBL3684902 | 0.66 | ESR2 (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210524-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2010-08-19 | — | — | US | claimed |
| EP-2176209-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2010-04-21 | — | — | EP | claimed |
| WO-2009012954-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-01-29 | — | — | WO | claimed |
| US-7816548-B2 | Method of preparing a hydrocarbylated metal-organic compound | DSM IP ASSETS B.V. (NL) | 2010-10-19 | — | — | US | disclosed |
| US-20100210524-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2010-08-19 | — | — | US | disclosed |
| EP-2176209-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009012954-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2009-01-29 | — | — | WO | disclosed |
| US-20080124298-A1 | Antifouling Coating Composition and Its Use on Man Made Structures | AKZO NOBEL COATING INTERNATIONAL B.V. (NL) | 2008-05-29 | — | — | US | disclosed |
| US-20070112182-A1 | Method of preparing a hydrocarbylated metal-organic compound | DSM IP ASSETS B.V. (NL) | 2007-05-17 | — | — | US | disclosed |
| US-7012121-B2 | Delayed activity supported olefin polymerization catalyst compositions and method for making and using the same | BP CHEMICALS LIMITED (GB) | 2006-03-14 | — | — | US | disclosed |
| US-20040235646-A1 | Delayed activity supported olefin polymerization catalyst compositions and method for making and using the same | BP CHEMICAL LIMITED | 2004-11-25 | — | — | US | disclosed |
| US-6635597-B1 | L+ B-(C6F5)3(C10F7), where L is a cation and B- is a boron anion; addition polymerization catalyst | NORTHWESTERN UNIVERSITY | 2003-10-21 | — | — | US | disclosed |
| US-6528449-B1 | Polymerization catalysts such as /tertbutylamido/tetramethyl-cyclopentadienyl/ dimethylsilanetitanium 1,3-pentadiene and isobutyl(perfluorophenyl)-4,6-di-(t-butyl) phenoxyaluminum | THE DOW CHEMICAL COMAPNY | 2003-03-04 | — | — | US | disclosed |
| US-6482896-B2 | FIBERS; BLEND OF POLYPROPYLENE AND ETHYLENE COPOLYMER | DOW GLOBAL TECHNOLOGIES INC. | 2002-11-19 | — | — | US | disclosed |
| US-20020132729-A1 | Catalyst activators comprising expanded anions | LAPOINTE ROBERT E (US) | 2002-09-19 | — | — | US | disclosed |
| US-20010027161-A1 | Catalyst activators comprising expanded anions | THE DOW CHEMICAL COMPANY | 2001-10-04 | — | — | US | disclosed |
| US-6291614-B1 | AS CATALYST ACTIVATOR ADAPTED FOR USE IN THE ACTIVATION OF METAL COMPLEXES POLYMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS SUCH AS OLEFINS | THE DOW CHEMICAL COMPANY | 2001-09-18 | — | — | US | disclosed |
| US-20010018396-A1 | Activator composition comprising aluminum compound mixture | CHEN EUGENE Y (US) | 2001-08-30 | — | — | US | disclosed |
| US-6268445-B1 | AROMATIC BORANE AND FLUOROBORON COMPOUNDS AS PROMOTERS | THE DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210524-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | ESR1, ESRRA, ESR2 | MAPT 4240/4885POLB 4529/4885KDM4E 572/4885 |
| US-20070112182-A1 | Method of preparing a hydrocarbylated metal-organic compound | DRD2, DRD1, DRD4 | MAPT 4199/4885POLB 3639/4885KDM4E 111/4885 |
| US-20080124298-A1 | Antifouling Coating Composition and Its Use on Man Made Structures | SOD1, ITGAV, ITGA2B | MAPT 1904/4885POLB 190/4885KDM4E 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.